Photocycles of channelrhodopsin-2.

@article{Nikolic2009PhotocyclesOC,
  title={Photocycles of channelrhodopsin-2.},
  author={Konstantin Nikolic and Nir Grossman and Matthew S Grubb and Juan Burrone and Chris Toumazou and Patrick Degenaar},
  journal={Photochemistry and photobiology},
  year={2009},
  volume={85 1},
  pages={
          400-11
        }
}
Recent developments have used light-activated channels or transporters to modulate neuronal activity. One such genetically-encoded modulator of activity, channelrhodopsin-2 (ChR2), depolarizes neurons in response to blue light. In this work, we first conducted electrophysiological studies of the photokinetics of hippocampal cells expressing ChR2, for various light stimulations. These and other experimental results were then used for systematic investigation of the previously proposed three… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 25 REFERENCES

A Non-Invasive Retinal Prosthesis - Testing the Concept

  • 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
  • 2007
VIEW 1 EXCERPT

High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2007
VIEW 1 EXCERPT