Photocrosslinkable kappa-carrageenan hydrogels for tissue engineering applications.

  title={Photocrosslinkable kappa-carrageenan hydrogels for tissue engineering applications.},
  author={Silvia M. Mihaila and Akhilesh K Gaharwar and Rui Lu{\'i}s Reis and Alexandra Pinto Marques and Manuela Estima Gomes and Ali Khademhosseini},
  journal={Advanced healthcare materials},
  volume={2 6},
Kappa carrageenan (κ-CA) is a natural-origin polymer that closely mimics the glycosaminoglycan structure, one of the most important constituents of native tissues extracellular matrix. Previously, it has been shown that κ-CA can crosslink via ionic interactions rendering strong, but brittle hydrogels. In this study, we introduce photocrosslinkable methacrylate moieties on the κ-CA backbone to create physically and chemically crosslinked hydrogels highlighting their use in the context of tissue… CONTINUE READING
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