Photochemical genotoxicity: principles and test methods. Report of a GUM task force.

@article{BrendlerSchwaab2004PhotochemicalGP,
  title={Photochemical genotoxicity: principles and test methods. Report of a GUM task force.},
  author={Susanne Y. Brendler-Schwaab and Andreas Czich and Bernd Epe and Elmar Gocke and Bernd Kaina and Lutz M{\"u}ller and Dieter Pollet and Dietmar Utesch},
  journal={Mutation research},
  year={2004},
  volume={566 1},
  pages={65-91}
}
In recent years, assessing the photogenotoxic potential of a compound became an issue for certain drugs and cosmetical products. Therefore, existing methods performed according to international guidelines (e.g. OECD guidelines) were adapted to the use of concurrent UV-visible (UV-Vis) light irradiation for the assessment of photomutagenicity/photogenotoxicity. In this review, photobiological bases of the processes occurring in the cell after irradiation with UV- and/or visible (vis)-light as… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

Comparative study on prediction performance of photosafety testing tools on photoallergens.

Toxicology in vitro : an international journal published in association with BIBRA • 2016
View 3 Excerpts

Non-animal photosafety assessment approaches for cosmetics based on the photochemical and photobiochemical properties.

Toxicology in vitro : an international journal published in association with BIBRA • 2013

The rise and fall of photomutagenesis.

Mutation research • 2013
View 4 Excerpts

Similar Papers

Loading similar papers…