Photochemical Synthesis of a Pyridopyrrolo [2, 1-α] isoindole System by Cyclization of N-Methylpyridylphthalimides

  title={Photochemical Synthesis of a Pyridopyrrolo [2, 1-$\alpha$] isoindole System by Cyclization of N-Methylpyridylphthalimides},
  author={M. Terashima and K. Seki and K. K{\^o}yama and Y. Kanaoka},
  journal={Chemical \& Pharmaceutical Bulletin},
Photochemical reactions of N-methylpyridylphthalimides (VII-IX) were investigated. Although irradiation of VII in an acetone solution gave only the dihydro product, 3-hydroxy-2-(3-methyl-2-pyridyl) phthalimidine (X), VIII afforded the expected cyclized product, 10b, 11-dihydro-10b-hydroxy-6H-pyrido [4', 3' : 4, 5] pyrrolo [2, 1-a] isoindol-6-one (XII) and dihydro product, 3-hydroxy-2-(4-methyl-3-pyridyl) phthalimidine (XI). Under similar conditions, the cyclized product, 10b, 11-dihydro-10b… Expand
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