Photobactericidal activity of phenothiazinium dyes against methicillin-resistant strains of Staphylococcus aureus.

  title={Photobactericidal activity of phenothiazinium dyes against methicillin-resistant strains of Staphylococcus aureus.},
  author={M. Wainwright and D. Phoenix and S. Laycock and D. Wareing and P. Wright},
  journal={FEMS microbiology letters},
  volume={160 2},
  • M. Wainwright, D. Phoenix, +2 authors P. Wright
  • Published 1998
  • Biology, Medicine
  • FEMS microbiology letters
  • The photodynamic antibacterial properties of a closely related series of phenothiazinium dyes were tested against several pathogenic strains of Staphylococcus aureus, four of which were methicillin-resistant. Illumination of the photosensitisers at a fluence rate of 1.75 mW cm-2 generally resulted in the enhancement of antibacterial activity in liquid culture and in greater efficacy than the methicillin analogue flucloxacillin. For methylene blue, dimethyl methylene blue and new methylene blue… CONTINUE READING
    193 Citations

    Topics from this paper.

    Phenothiazinium Antimicrobial Photosensitizers Are Substrates of Bacterial Multidrug Resistance Pumps
    • 166
    • PDF
    Comparative Photodynamic Evaluation of New Phenothiazinium Derivatives against Propionibacterium acnes †
    • 18
    A comparative in vitro photoinactivation study of clinical isolates of multidrug-resistant pathogens
    • H. M. Tang, M. Hamblin, C. M. Yow
    • Biology, Medicine
    • Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
    • 2007
    • 97
    Photodynamic activity of water-soluble phthalocyanine zinc(II) complexes against pathogenic microorganisms.
    • 106


    A study of photobactericidal activity in the phenothiazinium series.
    • 149
    • PDF
    In-vitro photobactericidal activity of aminoacridines.
    • 29
    • PDF
    Increased cytotoxicity and phototoxicity in the methylene blue series via chromophore methylation.
    • 137
    Expression of resistance to methicillin.
    • 94
    A major outbreak of methicillin-resistant Staphylococcus aureus caused by a new phage-type (EMRSA-16)
    • 261
    The estimation of the bactericidal power of the blood.
    • 3,038
    • PDF
    Characterization of superoxide dismutase genes from gram-positive bacteria by polymerase chain reaction using degenerate primers.
    • 73
    • PDF