Photoallergic Drug Eruption Due to Pyridoxine Hydrochloride

  title={Photoallergic Drug Eruption Due to Pyridoxine Hydrochloride},
  author={M. Tanaka and Hironori Niizeki and Satoko Shimizu and Shun‐ichi Miyakawa},
  journal={The Journal of Dermatology},
Photoallergy to vitamin B6 is very rare; only a few cases of contact dermatitis and one case of photosensitive dermatitis due to pyritinol have been reported. We report here the first case of photoallergy drug eruption due to pyridoxine hydrochloride. 
6 Citations
Occupational contact dermatitis due to pyritinol
A 17-year-old laboratory assistant, 4 months after starting to work on quality control in a pharmaceutical company, developed eczema on the face and hands, which coincided with working on pyritinol and other derivatives of pyridoxine used in the synthesis of Encephabol® (pyrit inol hydrochloride).
Pyridoxine-Induced Photosensitivity and Hypophosphatasia
The seric pyridoxal 5′-phosphate level of this patient with hypophosphatasia was higher than in normals, and after oral administration of vitamin B6 this level increased greatly and long-lastingly, and this might be related to the low level of alkaline phosphatase in this patient.
Photopatch Testing in Seven Cases of Photosensitive Drug Eruptions
Although there is no information about the appropriate concentrations or vehicles for suspected drugs, photopatch testing could be reliable for identification of causes of photosensitive drug eruptions.
Induction of contact sensitization to monotertiary butyl hydroquinone
A comparison of pyritinol and auranofin in the treatment of rheumatoid arthritis and contact sensitization to pyridine derivatives: Contact Dermatitis 1996: 35: 100-101 is presented.
The problem of hypersensitivity to vitamin preparations
The problem of determining the true allergic reaction in patients who report the development of a history of HS to VP remains relevant, and insufficiently developed methods of allergodiagnostics both in vivo (skin, provocative tests), and in vitro (laboratory tests) among patients with suspicion for the developmentof HS toVP are needed.
Immediate-type hypersensitivity to pyridoxal 5'-phosphate: Study of in vivo and in vitro cross-reactivity and identification of the antigenic determinant
In this very rare case, phosphate radical conjugates with a pyridine nucleus became haptenic-epitope and an immediate-type reaction occurred in a 45-year-old female patient with peritonitis after administration of preparations containing six different medications.


Photosensitive dermatitis due to pyritinol.
Lichen planus-like photosensitive dermatitis due to pyritinol hydrochloride occurred in a 62-year-old man, and the photopatch test was positive, considered to be due to photoallergy.
Allergic contact dermatitis to pyridoxine ester and hinokitiol
A case of allergic contact dermatitis caused by pyridoxine 3,4‐dioctanoate and hinokitiol is reported. The patient was also sensitized to pyridoxine hydrochloride.
Contact allergy to hydrocortisone 17‐butyrate and pyridoxine hydrochloride
3. Lymphographische Untersuchungen ohne Farbstoffmarkierung bei Patent-Blau-Allergie, cited in Sinclair D J, Perera F A, and Sieber F R.