Photoageing: mechanism, prevention and therapy.

  title={Photoageing: mechanism, prevention and therapy.},
  author={Mina Yaar and B. A. Gilchrest},
  journal={The British journal of dermatology},
  volume={157 5},
Photoageing is the superposition of chronic ultraviolet (UV)-induced damage on intrinsic ageing and accounts for most age-associated changes in skin appearance. It is triggered by receptor-initiated signalling, mitochondrial damage, protein oxidation and telomere-based DNA damage responses. Photodamaged skin displays variable epidermal thickness, dermal… CONTINUE READING