Photoaffinity labeling of the alpha 1-adrenergic receptor using an 125I-labeled aryl azide analogue of prazosin.

@article{Seidman1984PhotoaffinityLO,
  title={Photoaffinity labeling of the alpha 1-adrenergic receptor using an 125I-labeled aryl azide analogue of prazosin.},
  author={Christine E Seidman and H. J. Hess and Charles J. Homcy and Robert M. Graham},
  journal={Biochemistry},
  year={1984},
  volume={23 16},
  pages={3765-70}
}
alpha 1-Adrenergic receptor probes, which can be radioiodinated to yield high specific activity radioligands, have been synthesized and characterized. 2-[4-(4-Amino-benzoyl)piperazin-1-yl]-4-amino-6,7-dimethoxyquin azoline (CP63,155), an arylamine analogue of the selective alpha 1-adrenergic antagonist prazosin, and its iodinated derivative, 2-[4-(4-amino-3… CONTINUE READING