Photoactivation of ROS Production In Situ Transiently Activates Cell Proliferation in Mouse Skin and in the Hair Follicle Stem Cell Niche Promoting Hair Growth and Wound Healing.

@article{Carrasco2015PhotoactivationOR,
  title={Photoactivation of ROS Production In Situ Transiently Activates Cell Proliferation in Mouse Skin and in the Hair Follicle Stem Cell Niche Promoting Hair Growth and Wound Healing.},
  author={Elisa Carrasco and Mar{\'i}a Inmaculada Calvo and Alfonso Bl{\'a}zquez-Castro and Daniela Vecchio and Alicia Zamarr{\'o}n and Irma Joyce Dias de Almeida and Juan Carlos Stockert and Michael R Hamblin and Angeles Juarranz and Jes{\'u}s Espada},
  journal={The Journal of investigative dermatology},
  year={2015},
  volume={135 11},
  pages={2611-2622}
}
The role of reactive oxygen species (ROS) in the regulation of hair follicle (HF) cycle and skin homeostasis is poorly characterized. ROS have been traditionally linked to human disease and aging, but recent findings suggest that they can also have beneficial physiological functions in vivo in mammals. To test this hypothesis, we transiently switched on in situ ROS production in mouse skin. This process activated cell proliferation in the tissue and, interestingly, in the bulge region of the HF… CONTINUE READING