Photoacoustic “nanobombs” fight against undesirable vesicular compartmentalization of anticancer drugs

Abstract

Undesirable intracellular vesicular compartmentalization of anticancer drugs in cancer cells is a common cause of chemoresistance. Strategies aimed at circumventing this problem may improve chemotherapeutic efficacy. We report a novel photophysical strategy for controlled-disruption of vesicular sequestration of the anticancer drug doxorubicin (DOX). Single… (More)
DOI: 10.1038/srep15527

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