Photo-oxidative killing of human colonic cancer cells using indocyanine green and infrared light

@inproceedings{Bumler1999PhotooxidativeKO,
  title={Photo-oxidative killing of human colonic cancer cells using indocyanine green and infrared light},
  author={Wolfgang B{\"a}umler and Christoph Abels and Sigrid Karrer and Thomas S. Weiss and Helmut Messmann and M{\'i}chael Landthaler and R M Szeimies},
  booktitle={British Journal of Cancer},
  year={1999}
}
SummaryDespite of the approval of Photofrin® in various countries, chemically defined sensitizers for photodynamic therapy (PDT) are still needed for the absorption of light in the infrared spectrum, which provides a maximal penetration of light into tissue. Therefore, both the efficacy and the mechanism of action of the clinically approved dye indocyanine green (ICG) and laser irradiation were investigated in vitro. For the investigation of phototoxic effects, HT-29 cells were incubated 24 h… CONTINUE READING

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