Photo-induced radical thiol-ene chemistry: a versatile toolbox for peptide-based drug design.

  title={Photo-induced radical thiol-ene chemistry: a versatile toolbox for peptide-based drug design.},
  author={Marzieh Ahangarpour and Iman Kavianinia and Paul W. R. Harris and Margaret A. Brimble},
  journal={Chemical Society reviews},
While the global market for peptide/protein-based therapeutics is witnessing significant growth, the development of peptide drugs remains challenging due to their low oral bioavailability, poor membrane permeability, and reduced metabolic stability. However, a toolbox of chemical approaches has been explored for peptide modification to overcome these obstacles. In recent years, there has been a revival of interest in photoinduced radical thiol-ene chemistry as a powerful tool for the… 
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