Photo-cross-linked hydrogels with polysaccharide-poly(amino acid) structure: new biomaterials for pharmaceutical applications.

@article{Pitarresi2006PhotocrosslinkedHW,
  title={Photo-cross-linked hydrogels with polysaccharide-poly(amino acid) structure: new biomaterials for pharmaceutical applications.},
  author={Giovanna Pitarresi and Paola Pierro and Fabio Palumbo and Giuseppe Tripodo and Gaetano Giammona},
  journal={Biomacromolecules},
  year={2006},
  volume={7 4},
  pages={1302-10}
}
The aim of this work has been the preparation and characterization of novel hydrogels with polysaccharide-poly(amino acid) structure having suitable physicochemical properties for pharmaceutical applications. In the first step, hyaluronic acid (HA) and alpha,beta-poly(N-2-hydroxyethyl)-DL-aspartamide (PHEA) have been derivatized with methacrylic anhydride (AMA), thus obtaining HA-AMA and PHM derivatives, respectively. In the second step, aqueous solutions of both these derivatives have been… CONTINUE READING
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