Photo-Switching of Protein Dynamical Collectivity

  title={Photo-Switching of Protein Dynamical Collectivity},
  author={M Xu and Deepu K. George and Ralph Jimenez and Andrea G. Markelz},
We examine changes in the picosecond structural dynamics with irreversible photobleaching of red fluorescent proteins (RFP) mCherry, mOrange2 and TagRFP-T. Measurements of the protein dynamical transition using terahertz time-domain spectroscopy show in all cases an increase in the turn-on temperature in the bleached state. The result is surprising given that there is little change in the protein surface, and thus, the solvent dynamics held responsible for the transition should not change. A… 
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