Photo-Dimerization Induced Dynamic Viscoelastic Changes in ABA Triblock Copolymer-Based Hydrogels for 3D Cell Culture

@article{Tamate2016PhotoDimerizationID,
  title={Photo-Dimerization Induced Dynamic Viscoelastic Changes in ABA Triblock Copolymer-Based Hydrogels for 3D Cell Culture},
  author={R. Tamate and T. Ueki and Yuzo Kitazawa and Morinobu Kuzunuki and Masayoshi Watanabe and A. Akimoto and R. Yoshida},
  journal={Chemistry of Materials},
  year={2016},
  volume={28},
  pages={6401-6408}
}
Cells sense and respond not only to biochemical signals but also to biophysical signals (e.g., matrix elasticity). In addition to matrix elasticity, recent studies have revealed that viscoelasticity (e.g., stress relaxation) significantly affects cellular functions, such as spreading, proliferation, and differentiation. Herein, we describe a cytocompatible and dynamic hydrogel that is comprised of well-defined ABA triblock copolymers, which enable significant changes of viscoelastic properties… Expand
Bioinspired glycosaminoglycan hydrogels via click chemistry for 3D dynamic cell encapsulation.
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