Phosphorylations of alpha A- and alpha B-crystallin.

  title={Phosphorylations of alpha A- and alpha B-crystallin.},
  author={Marc Kantorow and Joram Piatigorsky},
  journal={International journal of biological macromolecules},
  volume={22 3-4},
In addition to being refractive proteins in the vertebrate lens, the two alpha-crystallin polypeptides (alpha A and alpha B) are also molecular chaperones that can protect proteins from thermal aggregation. The alpha B-crystallin polypeptide, a functional member of the small heat shock family, is expressed in many tissues in a developmentally regulated fashion, is stress-inducible, and is overexpressed in many degenerative diseases and some tumors indicating that it plays multiple roles. One… CONTINUE READING
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