Phosphorylation of the M3/6 dual-specificity phosphatase enhances the activation of JNK by arsenite.

Abstract

Specific outcomes upon activation of the c-Jun N-terminal kinase (JNK) pathway critically depend on the intensity and duration of signal transmission. Dual-specificity phosphatases (DUSPs) play a very important role in these events by modulating the extent of JNK phosphorylation and activation and thus regulating cellular responses to stress. M3/6 (DUSP8… (More)
DOI: 10.1016/j.cellsig.2011.10.015

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@article{Cotsiki2012PhosphorylationOT, title={Phosphorylation of the M3/6 dual-specificity phosphatase enhances the activation of JNK by arsenite.}, author={Marina Cotsiki and Wolf Oehrl and Martina Samiotaki and Aspasia Theodosiou and George N Panayotou}, journal={Cellular signalling}, year={2012}, volume={24 3}, pages={664-76} }