Phosphorylation of the 19,000-dalton light chain of myosin in perfused rat heart under the influence of negative and positive inotropic agents.

@article{Kopp1979PhosphorylationOT,
  title={Phosphorylation of the 19,000-dalton light chain of myosin in perfused rat heart under the influence of negative and positive inotropic agents.},
  author={Stephen J. Kopp and Michael B{\'a}r{\'a}ny},
  journal={The Journal of biological chemistry},
  year={1979},
  volume={254 23},
  pages={1207-12}
}
The phosphorylation of myofibrillar proteins was studied in rat hearts perfused with [32P]orthophosphate under the influence of negative (M&‘, Cd2’, Pb2’, low Ca’+) and positive (isoproterenol, high Ca’+) inotropic agents. The following physiological parameters were recorded: active tension, spontaneous heart rate, perfusion flow rate, and electrocardiogram. Of these parameters, only the active tension was found to be correlated with protein phosphorylation. The incorporation of [32P]phosphate… CONTINUE READING
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References

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Membranes and Disease

  • R. W. Straub, J. Ferrero, P. Jirounek, G. J. Jones, A. Salamin
  • Physiol. (Land.) 248,
  • 1975

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