Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Ser157 in intact human platelets correlates with fibrinogen receptor inhibition.

@article{Horstrup1994PhosphorylationOF,
  title={Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Ser157 in intact human platelets correlates with fibrinogen receptor inhibition.},
  author={K Horstrup and Bernd Jablonka and Petra Hoenig-Liedl and Melitta Just and Kurt Kochsiek and Ulrich Walter},
  journal={European journal of biochemistry},
  year={1994},
  volume={225 1},
  pages={21-7}
}
Integrins and other adhesion receptors are essential components for outside-in and inside-out signaling through the cell membrane. The platelet glycoprotein IIb-IIIa (also known as fibrinogen receptor or integrin alpha IIb beta 3) is activated by platelet agonists, inhibited by cyclic-nucleotide-elevating agents, and is involved in the activation of protein tyrosine kinases including the 125-kDa focal adhesion kinase (pp125FAK). However, the molecular details of glycoprotein IIb-IIIa regulation… CONTINUE READING
70 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 70 extracted citations

Similar Papers

Loading similar papers…