Phosphorylation of Pyrimidine Deoxynucleoside Analog Diphosphates

Abstract

D-Nucleoside analogs, which are in the natural configuration, as well as the L-nucleoside analogs, are clinically relevant antiviral and anticancer agents. Metabolism of L-nucleoside analog diphosphates to the triphosphates, however, remains unexplored. Studies with recombinant nm23-H1 and -H2 isoforms indicated that L-nucleoside analog diphosphates were… (More)

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@inproceedings{Krishnan2002PhosphorylationOP, title={Phosphorylation of Pyrimidine Deoxynucleoside Analog Diphosphates}, author={Preethi Sai Krishnan and Qin Fu and Wing Lam and J. N. Liou and Ginger E. Dutschman and Yung-chi Cheng}, year={2002} }