Phosphorylation of Not4p Functions Parallel to BUR2 to Regulate Resistance to Cellular Stresses in Saccharomyces cerevisiae

Abstract

BACKGROUND The evolutionarily conserved Ccr4-Not and Bur1/2 kinase complexes are functionally related in Saccharomyces cerevisiae. In this study, we further explore the relationship between the subunits Not4p and Bur2p. METHODOLOGY/PRINCIPAL FINDINGS First, we investigated the presence of post-translational modifications on the Ccr4-Not complex. Using… (More)
DOI: 10.1371/journal.pone.0009864

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