Phosphorylation of ERK in neurokinin 1 receptor-expressing neurons in laminae III and IV of the rat spinal dorsal horn following noxious stimulation

@article{Urban2007PhosphorylationOE,
  title={Phosphorylation of ERK in neurokinin 1 receptor-expressing neurons in laminae III and IV of the rat spinal dorsal horn following noxious stimulation},
  author={Laszlo Urban and Annie D Campbell and Lynsey M MacIntyre and Masanori Watanabe and Andrew J Todd},
  journal={Molecular Pain},
  year={2007},
  volume={3},
  pages={4 - 4}
}
BackgroundThere is a population of large neurons with cell bodies in laminae III and IV of the spinal dorsal horn which express the neurokinin 1 receptor (NK1r) and have dendrites that enter the superficial laminae. Although it has been shown that these are all projection neurons and that they are innervated by substance P-containing (nociceptive) primary afferents, we know little about their responses to noxious stimuli. In this study we have looked for phosphorylation of extracellular signal… CONTINUE READING
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