Phosphorylation-independent bacterial chemoresponses correlate with changes in the cytoplasmic level of fumarate.

@article{Montrone1996PhosphorylationindependentBC,
  title={Phosphorylation-independent bacterial chemoresponses correlate with changes in the cytoplasmic level of fumarate.},
  author={Michele Montrone and Dieter Oesterhelt and Wolfgang Marwan},
  journal={Journal of bacteriology},
  year={1996},
  volume={178 23},
  pages={6882-7}
}
Bacterial chemotaxis is based on modulation of the probability to switch the direction of flagellar rotation. Responses to many stimuli are transduced by a two-component system via reversible phosphorylation of CheY, a small cytoplasmic protein that directly interacts with the switch complex at the flagellar motor. We found that the chemorepellents indole and benzoate induce motor switching in Escherichia coli cells with a disabled phosphorylation cascade. This phosphorylation-independent… CONTINUE READING