Phosphorylation-independent activity of atypical response regulators of Helicobacter pylori.

@article{Schaer2005PhosphorylationindependentAO,
  title={Phosphorylation-independent activity of atypical response regulators of Helicobacter pylori.},
  author={J. Schaer and Albert Sickmann and Dagmar Beier},
  journal={Journal of bacteriology},
  year={2005},
  volume={187 9},
  pages={3100-9}
}
The genome of the gastric pathogen Helicobacter pylori harbors a remarkably low number of regulatory genes, including three and five open reading frames encoding two-component histidine kinases and response regulators, respectively, which are putatively involved in transcriptional regulation. Two of the response regulator genes, hp1043 and hp166, proved to be essential for cell growth, and inactivation of the response regulator gene hp1021 resulted in a severe growth defect, as indicated by a… CONTINUE READING

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