Phosphorylation-dependent regulation of stability and transforming potential of ETS transcriptional factor ESE-1 by p21-activated kinase 1.

Abstract

Differential phosphorylation of transcription factors by signal transduction pathways play an important role in regulation of gene expression and functions. ESE-1 is an epithelium-specific ETS transcription factor that transforms human breast epithelial cells through a serine- and aspartic acid-rich domain (SAR) by an unknown cytoplasmic mechanism. Here we… (More)

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@article{Manavathi2007PhosphorylationdependentRO, title={Phosphorylation-dependent regulation of stability and transforming potential of ETS transcriptional factor ESE-1 by p21-activated kinase 1.}, author={Bramanandam Manavathi and Suresh Kumar Rayala and Rakesh Kumar}, journal={The Journal of biological chemistry}, year={2007}, volume={282 27}, pages={19820-30} }