Phosphorylated tau/amyloid beta 1-42 ratio in ventricular cerebrospinal fluid reflects outcome in idiopathic normal pressure hydrocephalus

@inproceedings{Patel2011PhosphorylatedTB,
  title={Phosphorylated tau/amyloid beta 1-42 ratio in ventricular cerebrospinal fluid reflects outcome in idiopathic normal pressure hydrocephalus},
  author={Sunil Patel and Edward K. B. Lee and Sharon X Xie and Anica C Law and E M Jackson and Steven E Arnold and C. M. Clark and Leslie M. Shaw and Michael S Grady and John Q. Trojanowski and Roy Hamilton},
  booktitle={Fluids and Barriers of the CNS},
  year={2011}
}
Idiopathic normal pressure hydrocephalus (iNPH) is a potentially reversible cause of dementia and gait disturbance that is typically treated by operative placement of a ventriculoperitoneal shunt. The outcome from shunting is variable, and some evidence suggests that the presence of comorbid Alzheimer's disease (AD) may impact shunt outcome. Evidence also suggests that AD biomarkers in cerebrospinal fluid (CSF) may predict the presence of AD. The aim of this study was to investigate the… CONTINUE READING
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Cortical biopsy and empirical post-operative shunt valve programming: a novel treatment approach to idiopathic normal pressure hydrocephalus

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1 Excerpt

CSF biomarker signature in AD neuroimaging initiative subjects

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