Phosphorylated cAMP response element binding protein in the mouse brain after fear conditioning: relationship to Fos production.

@article{Stanciu2001PhosphorylatedCR,
  title={Phosphorylated cAMP response element binding protein in the mouse brain after fear conditioning: relationship to Fos production.},
  author={Monica Stanciu and Jelena Radulovic and Joanchim Spiess},
  journal={Brain research. Molecular brain research},
  year={2001},
  volume={94 1-2},
  pages={15-24}
}
Phosphorylation of the cAMP response element binding protein (pCREB) triggered by associative learning was monitored immunohistochemically in different areas of the mouse brain during a 6-h interval, starting immediately after training. One trial context-dependent fear conditioning was employed as a learning paradigm. Training consisted of contextual exposure followed by shock. Control groups consisted of naïve mice, mice exposed to the context alone and mice exposed to an immediate shock in… CONTINUE READING