Phosphorylated Mnk1 and eIF4E Are Associated with Lymph Node Metastasis and Poor Prognosis of Nasopharyngeal Carcinoma

Abstract

Nasopharyngeal carcinoma (NPC) is a head and neck malignant tumor rare throughout most of the world but common in Southeast Asia, especially in Southern China. The phosphorylation of eukaryotic translation initiation factor 4E (eIF4E) by MAP kinase-interacting kinases (Mnk) on Ser-209 promotes cellular proliferation, survival, malignant transformation and… (More)
DOI: 10.1371/journal.pone.0089220

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Cite this paper

@inproceedings{Zheng2014PhosphorylatedMA, title={Phosphorylated Mnk1 and eIF4E Are Associated with Lymph Node Metastasis and Poor Prognosis of Nasopharyngeal Carcinoma}, author={Jun Zheng and Jiao Li and Lina Xu and Guiyuan Xie and Qiuyuan Wen and Jiadi Luo and Duo Li and Donghai Huang and Songqing Fan}, booktitle={PloS one}, year={2014} }