Phosphorylated H2AX foci in tumor cells have no correlation with their radiation sensitivities.

Abstract

Ionizing radiation causes DNA double strand breaks (DSBs), which produce a chromosomal change with the modification of chromatin protein. The histone H2AX is phosphorylated, and phosphorylated H2AX makes a focus. The phosphorylated H2AX focus is regarded as recruiting mediators of repair factors of DNA DSBs. Although most of the initial phosphorylated H2AX… (More)

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Cite this paper

@article{Yoshikawa2009PhosphorylatedHF, title={Phosphorylated H2AX foci in tumor cells have no correlation with their radiation sensitivities.}, author={Tomohiro Yoshikawa and Genro Kashino and Koji Ono and Masami Watanabe}, journal={Journal of radiation research}, year={2009}, volume={50 2}, pages={151-60} }