Phosphorylated 4E-binding protein 1 (p-4E-BP1): a novel prognostic marker in human astrocytomas.

Abstract

AIMS To investigate the significance of the mammalian target of rapamycin (mTOR) pathway in astrocytic tumours, published information in this context being limited, especially regarding phosphorylated 4E-binding protein (p-4E-BP) 1. METHODS AND RESULTS Paraffin-embedded tissue from 111 patients with astroglial tumours (grades II-IV) was investigated for… (More)
DOI: 10.1111/j.1365-2559.2012.04236.x

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