Phosphorylated 4E binding protein 1: a hallmark of cell signaling that correlates with survival in ovarian cancer.

@article{Castellv2006Phosphorylated4B,
  title={Phosphorylated 4E binding protein 1: a hallmark of cell signaling that correlates with survival in ovarian cancer.},
  author={Josep Castellv{\'i} and Angel Garcia and Federico Cuesta Rojo and Carmen Ru{\'i}z-Marcell{\'a}n and Antonio Gil and Jos{\'e} Baselga and Santiago Ramon Y Cajal},
  journal={Cancer},
  year={2006},
  volume={107 8},
  pages={1801-11}
}
BACKGROUND Growth factor receptors and cell signaling factors play a crucial role in human carcinomas and have been studied in ovarian tumors with varying results. Cell signaling involves multiple pathways and a myriad of factors that can be mutated or amplified. Cell signaling is driven through the mammalian target of rapamycin (mTOR) and extracellular regulated kinase (ERK) pathways and by some downstream molecules, such as 4E binding protein 1 (4EBP1), eukaryotic initiation factor 4E, and… CONTINUE READING
92 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 92 extracted citations

Similar Papers

Loading similar papers…