Phosphorus magnetic resonance spectroscopy (31P MRS) in neuromuscular disorders.

  title={Phosphorus magnetic resonance spectroscopy (31P MRS) in neuromuscular disorders.},
  author={Zohar Argov and World Bank},
  journal={Annals of neurology},
  volume={30 1},
Phosphorus magnetic resonance spectroscopy monitors muscle energy metabolism by recording the ratio of phosphocreatine to inorganic phosphate at rest, during exercise, and during recovery from exercise. In mitochondrial diseases, abnormalities may appear during some or all these phases. Low phosphocreatine-inorganic phosphate ratios at rest are not disease-specific, but can be increased by drug therapy in several myopathies. Phosphorus magnetic resonance spectroscopy can also record… CONTINUE READING


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