Phosphoric Acid-Catalyzed Asymmetric Synthesis of SPINOL Derivatives.

Abstract

Axially chiral 1,1'-spirobiindane-7,7'-diol (SPINOL) is the most fundamental and important privileged structure from which other chiral ligands containing a 1,1'-spirobiindane backbone are synthesized. Driven by the development of enantioselective syntheses of axially chiral SPINOL derivatives, we have successfully developed the first phosphoric acid… (More)
DOI: 10.1021/jacs.6b11435

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