Phosphoregulation of Arp2/3-dependent actin assembly during receptor-mediated endocytosis

@article{Toshima2005PhosphoregulationOA,
  title={Phosphoregulation of Arp2/3-dependent actin assembly during receptor-mediated endocytosis},
  author={Jiro Toshima and Adam C. Martin and David G Drubin},
  journal={Nature Cell Biology},
  year={2005},
  volume={7},
  pages={246-254}
}
In both yeast and mammals, endocytic internalization is accompanied by a transient burst of actin polymerization. The yeast protein kinases Prk1p and Ark1p, which are related to the mammalian proteins GAK and AAK1, are key regulators of this process. However, the molecular mechanism(s) by which they regulate actin assembly at endocytic sites have not yet been determined. The Eps15-like yeast protein Pan1p is a Prk1p substrate that is essential for endocytic internalization and for proper actin… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 44 extracted citations

The yeast actin cytoskeleton: from cellular function to biochemical mechanism.

Microbiology and molecular biology reviews : MMBR • 2006
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-3 of 3 references

Implication of a novel multiprotein Dam1p complex in outer kinetochore function

Cheeseman, M I.
J Cell Biol 155, • 2001
View 2 Excerpts

Similar Papers

Loading similar papers…