Phosphoproteomics--finally fulfilling the promise?

  title={Phosphoproteomics--finally fulfilling the promise?},
  author={Lindsay D. Rogers and Leonard J. Foster},
  journal={Molecular bioSystems},
  volume={5 10},
Networks of protein-protein and protein-metabolite interactions are commonly found in biological systems where signals must be passed from one location or component within a cell to another, such as from a receptor on the plasma membrane to a transcription factor in the nucleus. Regulation of such networks, or signal transduction pathways, is often achieved by transient, reversible modification of the components involved. Several types of post-translational modifications of proteins are… CONTINUE READING