Phosphoproteomic Analysis of the Developing Mouse Brain*S

  title={Phosphoproteomic Analysis of the Developing Mouse Brain*S},
  author={B. A. Ballif and J. Vill{\'e}n and S. Beausoleil and D. Schwartz and S. Gygi},
  journal={Molecular & Cellular Proteomics},
  pages={1093 - 1101}
  • B. A. Ballif, J. Villén, +2 authors S. Gygi
  • Published 2004
  • Chemistry, Medicine
  • Molecular & Cellular Proteomics
  • Proper development of the mammalian brain requires the precise integration of numerous temporally and spatially regulated stimuli. Many of these signals transduce their cues via the reversible phosphorylation of downstream effector molecules. Neuronal stimuli acting in concert have the potential of generating enormous arrays of regulatory phosphoproteins. Toward the global profiling of phosphoproteins in the developing brain, we report here the use of a mass spectrometry-based methodology… CONTINUE READING
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