Phospholipids affect the intestinal absorption of carotenoids in mice

  title={Phospholipids affect the intestinal absorption of carotenoids in mice},
  author={Villikannan Baskaran and Tatsuya Sugawara and Akihiko Nagao},
Previously, we have shown that uptake of carotenoids solubilized with mixed micelles by human intestinal Caco-2 cells is enhanced by lysophosphatidylcholine (lysoPC) and suppressed by PC. This study determined the effect of PC and lysoPC in mixed micelles on the accumulation of β-carotene and lutein in mice in order to elucidate the roles of micellar phospholipid in the intestinal uptake of carotenoids in vivo. Mixed micelles were composed of 2.5 mM monooleoylglycerol, 7.5 mM oleic acid, 12 mM… CONTINUE READING
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