Phospholipids: Pulling Back the Actin Curtain for Granule Delivery to the Immune Synapse

@inproceedings{GawdenBone2019PhospholipidsPB,
  title={Phospholipids: Pulling Back the Actin Curtain for Granule Delivery to the Immune Synapse},
  author={Christian M. Gawden-Bone and Gillian M Griffiths},
  booktitle={Front. Immunol.},
  year={2019}
}
Phosphoinositides, together with the phospholipids phosphatidylserine and phosphatidic acid, are important components of the plasma membrane acting as second messengers that, with diacylglycerol, regulate a diverse range of signaling events converting extracellular changes into cellular responses. Local changes in their distribution and membrane charge on the inner leaflet of the plasma membrane play important roles in immune cell function. Here we discuss their distribution and regulators… CONTINUE READING

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