Phospholipid transfer is a prerequisite for PLTP-mediated HDL conversion.

  title={Phospholipid transfer is a prerequisite for PLTP-mediated HDL conversion.},
  author={Jarkko Huuskonen and Vesa M Olkkonen and Christian P Ehnholm and Jari Metso and Ilkka Julkunen and Matti S Jauhiainen},
  volume={39 51},
Phospholipid transfer protein (PLTP) is an important regulator of high-density lipoprotein (HDL) metabolism. The two main functions of PLTP are transfer of phospholipids between lipoprotein particles and modulation of HDL size and composition in a process called HDL conversion. These PLTP-mediated processes are physiologically important in the transfer of surface remnants from lipolyzed triglyceride-rich lipoproteins to nascent HDL particles and in the generation of prebeta-HDL, the initial… CONTINUE READING


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