Phospholipid scramblase: an update.

  title={Phospholipid scramblase: an update.},
  author={Edouard M. Bevers and Patrick L Williamson},
  journal={FEBS letters},
  volume={584 13},
The best understood consequence of the collapse of lipid asymmetry is exposure of phosphatidylserine (PS) in the external leaflet of the plasma membrane bilayer, where it is known to serve at least two major functions: providing a platform for development of the blood coagulation cascade and presenting the signal that induces phagocytosis of apoptotic cells. Lipid asymmetry is collapsed by activation of phospholipid scramblase(s) that catalyze bidirectional transbilayer movement of the major… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 97 extracted citations

Structure and function of TMEM16 proteins (anoctamins).

Physiological reviews • 2014
View 4 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 69 references

A genome - wide linkage scan in German shepherd dogs localizes canine platelet procoagulant deficiency ( Scott syndrome ) to canine chromosome 27

G. Remenyi, R. Szasz, P. Friese, G. L. Dale

Similar Papers

Loading similar papers…