Phospholipid packing asymmetry in curved membranes detected by fluorescence spectroscopy.

@article{Bramhall1986PhospholipidPA,
  title={Phospholipid packing asymmetry in curved membranes detected by fluorescence spectroscopy.},
  author={John S. Bramhall},
  journal={Biochemistry},
  year={1986},
  volume={25 11},
  pages={3479-86}
}
There are distinct differences in the molecular packing of phospholipid molecules in the inner and outer membrane monolayers of small lipid vesicles; a small radius of curvature imparts an asymmetry to the interface between these two monolayers. I have used an amphiphilic fluorescent probe, N-[5-(dimethylamino)naphthalenyl-1-sulfonyl]glycine (dansylglycine), to determine if this asymmetry in molecular packing leads to the existence of different environments for fluorescent probes resident in… CONTINUE READING

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