Phospholipid composition of postmortem schizophrenic brain by 31P NMR spectroscopy.

@article{Pearce2009PhospholipidCO,
  title={Phospholipid composition of postmortem schizophrenic brain by 31P NMR spectroscopy.},
  author={John M. Pearce and Richard A. Komoroski and Robert E. Mrak},
  journal={Magnetic resonance in medicine},
  year={2009},
  volume={61 1},
  pages={28-34}
}
Cell membrane abnormalities due to changes in phospholipid (PL) composition and metabolism have been implicated in schizophrenia pathogenesis. That work has generally assessed membrane phospholipids from nonneural tissues such as erythrocytes and platelets. High-resolution (31)P NMR spectroscopy was used to characterize PLs of gray matter in postmortem brain for 20 schizophrenics, 20 controls, and 7 patients with other mental illnesses (psychiatric controls). Tissues from frontal, temporal, and… CONTINUE READING

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