Phospholipase Cgamma-Erk Axis in vascular endothelial growth factor-induced eukaryotic initiation factor 4E phosphorylation and protein synthesis in renal epithelial cells.

Abstract

Vascular endothelial growth factor (VEGF) increases protein synthesis and induces hypertrophy in renal tubular epithelial cells (Senthil, D., Choudhury, G. G., McLaurin, C., and Kasinath, B. S. (2003) Kidney Int. 64, 468-479). We examined the role of Erk1/2 MAP kinase in protein synthesis induced by VEGF. VEGF stimulated Erk phosphorylation that was… (More)

Topics

Cite this paper

@article{Mariappan2005PhospholipaseCA, title={Phospholipase Cgamma-Erk Axis in vascular endothelial growth factor-induced eukaryotic initiation factor 4E phosphorylation and protein synthesis in renal epithelial cells.}, author={Meenalakshmi M. Mariappan and Duraisamy Senthil and Kavithalakshmi S Natarajan and Goutam Ghosh Choudhury and Balakuntalam S Kasinath}, journal={The Journal of biological chemistry}, year={2005}, volume={280 31}, pages={28402-11} }