Phospholipase C delta-type consists of three isozymes: bovine PLCdelta2 is a homologue of human/mouse PLCdelta4.

@article{Irino2004PhospholipaseCD,
  title={Phospholipase C delta-type consists of three isozymes: bovine PLCdelta2 is a homologue of human/mouse PLCdelta4.},
  author={Yasuhiro Irino and Hiroyuki Cho and Yoshikazu Nakamura and Masamichi Nakahara and Masahiro Furutani and Pann Ghill Suh and Tadaomi Takenawa and Kiyoko Fukami},
  journal={Biochemical and biophysical research communications},
  year={2004},
  volume={320 2},
  pages={
          537-43
        }
}
To date, 12 phospholipase C (PLC) isozymes have been identified in mammals, and they are divided into five classes, beta-, gamma-, delta-, epsilon-, and zeta-type. PLCdelta-type is reported to be composed of four isozymes, PLCdelta1-delta4. Here we report that a screening for mouse PLCdelta2 from a BAC library with primers that amplify a specific region of bovine PLCdelta2 resulted in isolation of one clone containing the mouse PLCdelta4 gene. Furthermore, a database search revealed that there… CONTINUE READING

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