Phospholipase Cγ2 (PLCγ2) is key component in Dectin-2 signaling pathway, mediating anti-fungal innate immune responses.

Abstract

C-type lectin receptors (CLRs) such as Dectin-2 function as pattern recognition receptors to sense fungal infection. However, the signaling pathways induced by these receptors remain largely unknown. Previous studies suggest that the CLR-induced signaling pathway may utilize similar signaling components as the B cell receptor-induced signaling pathway… (More)
DOI: 10.1074/jbc.M111.307389

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Cite this paper

@article{Gorjestani2011PhospholipaseC, title={Phospholipase Cγ2 (PLCγ2) is key component in Dectin-2 signaling pathway, mediating anti-fungal innate immune responses.}, author={Sara Gorjestani and Mei -Ying Wong Yu and Bing Tang and Dekai Zhang and Demin Wang and Xin Lin}, journal={The Journal of biological chemistry}, year={2011}, volume={286 51}, pages={43651-9} }