Phospholipase A2 type II binds to extracellular matrix biglycan: modulation of its activity on LDL by colocalization in glycosaminoglycan matrixes.

@article{Sartipy1998PhospholipaseAT,
  title={Phospholipase A2 type II binds to extracellular matrix biglycan: modulation of its activity on LDL by colocalization in glycosaminoglycan matrixes.},
  author={Peter Sartipy and G{\"o}ran Bondjers and Eva Hurt-Camejo},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1998},
  volume={18 12},
  pages={1934-41}
}
We recently reported the presence of secretory, nonpancreatic phospholipase A2 type II (snpPLA2; EC 3.1.1.4) in human atherosclerotic arteries (Hurt-Camejo et al, Arterioscler Thromb Vasc Biol. 1997;17:300-309). SnpPLA2 may generate the proinflammatory products lysophospholipids and free fatty acids, thus contributing to atherogenesis when acting on low… CONTINUE READING