Phospholipase A2 inhibitors.

@article{GarciaGarcia2009PhospholipaseAI,
  title={Phospholipase A2 inhibitors.},
  author={Hector M. Garcia-Garcia and Patrick W.J. Serruys},
  journal={Current opinion in lipidology},
  year={2009},
  volume={20 4},
  pages={
          327-32
        }
}
PURPOSE OF REVIEW As the role of lipids and inflammation in the genesis and progression of the atherosclerosis disease is unquestionable, novel treatment modalities that target both aspects are currently under investigation. RECENT FINDINGS For a long time atherosclerosis was regarded as a lipid-driven disease, but now it is evident that it also involves the simultaneous and combined effect of inflammation and immunological pathways. The secreted PLA2s and the lipoprotein-associated… CONTINUE READING
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