Phosphoinositol glycan derived mediators and insulin resistance. Prospects for diagnosis and therapy.

While much work remains, the evidence has become strong that IPG generation following insulin action is a significant signaling mechanism. A considerable body of data has established IPG release by insulin and other growth factors from cell membranes, cells and in human blood and muscle biopsies in vivo. Two separate IPG species containing D-chiro-inositol… CONTINUE READING