Phosphoinositides in cell regulation and membrane dynamics

@article{Paolo2006PhosphoinositidesIC,
  title={Phosphoinositides in cell regulation and membrane dynamics},
  author={Gilbert Di Paolo and Pietro De Camilli},
  journal={Nature},
  year={2006},
  volume={443},
  pages={651-657}
}
Inositol phospholipids have long been known to have an important regulatory role in cell physiology. The repertoire of cellular processes known to be directly or indirectly controlled by this class of lipids has now dramatically expanded. Through interactions mediated by their headgroups, which can be reversibly phosphorylated to generate seven species, phosphoinositides play a fundamental part in controlling membrane–cytosol interfaces. These lipids mediate acute responses, but also act as… 

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