Phosphoglyceride biosynthesis by brain microsomes: centrophenoxine, SaH-42-348, and DH-990 inhibit phospholipid N-methylation.

Abstract

The effects of centrophenoxine, SaH-42-348, and DH-990 on several enzymes involved in aminophospholipid biosynthesis in brain have been examined in vitro. Relatively high concentrations of centrophenoxine were required to achieve 50% inhibition of the microsomal enzymes CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase (EPT), CDP-choline:1… (More)

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@article{Percy1984PhosphoglycerideBB, title={Phosphoglyceride biosynthesis by brain microsomes: centrophenoxine, SaH-42-348, and DH-990 inhibit phospholipid N-methylation.}, author={Alan K. Percy and J. F. Moore and Charles J. Waechter}, journal={Archives of biochemistry and biophysics}, year={1984}, volume={235 1}, pages={18-25} }